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Diagnostic and Therapeutic Challenges Owing to Concurrent Pontine Glioma and Acute Lymphoblastic Leukemia

Anoop, Parameswaran MD, MRCPCH; Hargrave, Darren MRCP, MRCPCH; Zacharoulis, Stergios MD; Saran, Frank FRCP, FRCR

Journal of Pediatric Hematology/Oncology:
doi: 10.1097/MPH.0b013e318161aa4e
Clinical and Laboratory Observations
Abstract

The presence of 2 active primary tumors in a child is both unusual and challenging. This places the clinician and the family in a difficult situation while planning the treatment. The concurrent presence of a low-grade brain stem glioma and acute lymphoblastic leukemia in a genetically normal girl is presented. The problems encountered with diagnosis and treatment are discussed here.

Author Information

Department of Pediatric Hemato-Oncology, Royal Marsden Hospital, Downs Road, Sutton SM2 5PT, Surrey, UK

Reprints: Dr Darren Hargrave, MRCP, MRCPCH, Royal Marsden Hospital, Downs Road, Sutton SM2 5PT, Surrey, UK (e-mail: darren.hargrave@yahoo.co.uk).

Received for publication October 1, 2007; accepted October 31, 2007

© 2008 Lippincott Williams & Wilkins, Inc.