A 7-year-old boy was referred with a provisional diagnosis of bilateral Wilms tumor. Peripheral smear revealed elevated leukocyte count with 90% blasts. Bone marrow aspiration and biopsy were hypercellular with sheets of blasts. Immunohistochemistry on paraffin sections showed a pre-B phenotype of acute lymphoblastic leukemia. Computerized tomographic scan of the abdomen showed moderate bilateral renal enlargement. Ultrasound-guided fine needle aspiration cytology of both kidneys showed blasts similar to those seen in the bone marrow. Finally, a diagnosis of pre-B acute lymphoblastic leukemia infiltrating both the kidneys was made. This case is being presented because of its rarity.
Kidwai Memorial Institute of Oncology, Bangalore, Karnataka, India
Disclaimers: No disclaimers.
This study has not been presented anywhere else.
No research was undertaken. It is a case report.
Reprints: Rudramurthy Pradeep, MD, 1905, South end ‘C’ road, 9th block, Jayanagar, Bangalore 560069, Karnataka, India (e-mail: firstname.lastname@example.org).
Received for publication July 22, 2007; accepted January 2, 2008