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Burkitt Lymphoma Involving the Clivus

Aronson, Paul L. MD*; Reilly, Anne MD, MPH* †; Paessler, Michele MD‡ §; Kersun, Leslie S. MD, MSCE* †

Journal of Pediatric Hematology/Oncology: April 2008 - Volume 30 - Issue 4 - pp 320-321
doi: 10.1097/MPH.0b013e318162bd1c
Clinical and Laboratory Observations

Burkitt lymphoma (BL) is a rapidly dividing tumor that commonly presents itself in the jaw in its endemic form and the abdomen in the sporadic type. Central nervous system involvement at diagnosis is not uncommon, but there have been no previously published reports of BL involving the clivus. Increased tumor burden is associated with complications such as tumor lysis syndrome, and recognition of unusual presentations is important for timely management. We report 3 patients with BL involving the clivus at diagnosis.

Departments of *Pediatrics

Division of Oncology

Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA

§Pathology and Laboratory Medicine, The University of Pennsylvania School of Medicine

No sources of financial support were used for this work.

Reprints: Dr Leslie S. Kersun, MD, Division of Oncology, Children's Hospital of Philadelphia, 34th and Civic Center Boulevard, Philadelphia, PA 19104 (e-mail: segall@email.chop.edu).

Received for publication January 18, 2007; accepted November 12, 2007

© 2008 Lippincott Williams & Wilkins, Inc.