Skip Navigation LinksHome > June 2005 - Volume 27 - Issue 6 > Kikuchi-Fujimoto Disease Is a Rare Cause of Lymphadenopathy...
Journal of Pediatric Hematology/Oncology:
Clinical and Laboratory Observations

Kikuchi-Fujimoto Disease Is a Rare Cause of Lymphadenopathy and Fever of Unknown Origin in Children: Report of Two Cases and Review of the Literature

Scagni, Paola MD*; Peisino, Maria Grazia MD*; Bianchi, Maurizio MD†; Morello, Maura MD*; Sardi, Nicola MD†; Linari, Alessandra MD‡; Mastrodicasa, Luana MD†; Madon, Enrico MD†; Pecco, Paola MD*

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Kikuchi-Fujimoto disease, a benign and unusual self-limiting histiocytic necrotizing lymphadenitis of unknown origin, should be included in the differential diagnosis of lymphadenopathy and fever of unknown origin. This disease mostly affects young Asian women and has rarely been reported in children, thus remaining a poorly recognized entity that is frequently confused with malignant lymphoma. The authors describe two children with Kikuchi-Fujimoto disease, with particular attention to diagnostic approach and clinical and histologic features of the disease.

© 2005 Lippincott Williams & Wilkins, Inc.


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