Crohn's disease is characterized by chronic intestinal inflammation in the absence of a recognized etiology. Nutritional therapy in the form of exclusive enteral nutrition (EEN) has an established role within pediatric Crohn's disease. Following EEN's success, many dietary therapies focusing on the elimination of specific complex carbohydrates have been anecdotally reported to be successful. Many of these therapies have not been evaluated scientifically; therefore we reviewed the medical records of our patients with Crohn's disease on the Specific Carbohydrate Diet (SCD)(TM). Seven children with Crohn's on the SCD(TM) and on no immunosuppressive medications were retrospectively evaluated. Duration of the dietary therapy ranged from five months to thirty months, with an average of 14.6 +/- 10.8 months. Although the exact time of symptom resolution could not be determined through chart review, all symptoms were notably resolved at a routine clinic visit three months after initiating the diet. Each patient's laboratory indices, including serum albumin, C - reactive protein, hematocrit and stool calprotectin, either normalized or significantly improved during follow-up clinic visits. This chart review suggests that the SCD(TM) and other low complex carbohydrate diets may be possible therapeutic options for pediatric Crohn's disease. Further prospective studies are required to fully assess the safety and efficacy of the SCD(TM), or any other low complex specific carbohydrate diets in pediatric patients with Crohn's disease.
(C) 2013 by European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and North American Society for Pediatric Gastroenterology,