Skip Navigation LinksHome > August 2013 - Volume 57 - Issue 2 > Polyethylene Glycol: A Game-Changer Laxative for Children
Journal of Pediatric Gastroenterology & Nutrition:
doi: 10.1097/MPG.0b013e318296404a
Invited Reviews

Polyethylene Glycol: A Game-Changer Laxative for Children

Alper, Arik; Pashankar, Dinesh S.

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ABSTRACT: Constipation is a common problem in children worldwide. It can also be a chronic problem persisting for many months to years. Successful treatment of constipation requires long-term use of laxatives. Commonly used laxatives in children include milk of magnesia, lactulose, mineral oil, and polyethylene glycol. Compared with other laxatives, polyethylene glycol (with and without electrolytes) is a relatively new laxative used during the last decade. Recent studies report excellent efficacy and safety of polyethylene glycol for the long-term treatment of constipation in children. Because of excellent patient acceptance, polyethylene glycol has become a preferred choice of laxative for many practitioners. This article reviews the recently published pediatric literature on biochemistry, efficacy, safety, patient acceptance, and pharmacoeconomics of polyethylene glycol.

© 2013 by European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and North American Society for Pediatric Gastroenterology,


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