Skip Navigation LinksHome > June 2012 - Volume 54 - Issue 6 > NASPGHAN Practice Guidelines: Diagnosis and Management of H...
Text sizing:
A
A
A
Journal of Pediatric Gastroenterology & Nutrition:
doi: 10.1097/MPG.0b013e318258328d
Clinical Guideline

NASPGHAN Practice Guidelines: Diagnosis and Management of Hepatitis C Infection in Infants, Children, and Adolescents

Mack, Cara L.*; Gonzalez-Peralta, Regino P.; Gupta, Nitika; Leung, Daniel§; Narkewicz, Michael R.*; Roberts, Eve A.||; Rosenthal, Philip; Schwarz, Kathleen B.#

Supplemental Author Material
Collapse Box

Abstract

ABSTRACT: Hepatitis C virus (HCV) is an RNA virus that affects >180 million individuals worldwide with a high propensity for chronic infection. Children with HCV infection differ from adults in several ways including some modes of transmission, rates of clearance, progression of fibrosis, and the duration of potential chronic infection when acquired at birth. Since the discovery of HCV in 1989, there have been significant advances in the understanding of the virology and natural history of chronic HCV infection in children. In addition, there are now several treatment options for children with chronic hepatitis C infection and many new therapies on the horizon. As a consequence, the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition brought together experts in pediatric hepatology to review the available data in children and provide clinicians with approaches to the diagnosis, management, and prevention of HCV infection in children and adolescents. The guideline details the epidemiology and natural history of HCV infection in children, the diagnostic workup, monitoring and treatment of disease, and provides an update on future treatment options and areas of research.

Copyright 2012 by ESPGHAN and NASPGHAN

Login

Article Tools

Share

Article Level Metrics

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.

Connect With Us

 

 

Twitter

twitter.com/JPGNonline