Skip Navigation LinksHome > April 2012 - Volume 54 - Issue 4 > Brain-Gut Axis: From Basic Understanding to Treatment of IB...
Journal of Pediatric Gastroenterology & Nutrition:
doi: 10.1097/MPG.0b013e31823d34c3
Invited Reviews

Brain-Gut Axis: From Basic Understanding to Treatment of IBS and Related Disorders

Camilleri, Michael*; Di Lorenzo, Carlo

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ABSTRACT: The present review describes advances in understanding the mechanisms and provide an update of present and promising therapy directed at the gut or the brain in the treatment of irritable bowel syndrome (IBS). The diagnosis of IBS typically is based on identification of symptoms, such as the Rome III criteria for IBS in adults and children. The criteria are similar in children and adults. The focus of the present review is the bowel dysfunction associated with IBS.

Copyright 2012 by ESPGHAN and NASPGHAN


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