Skip Navigation LinksHome > November 2011 - Volume 53 - Issue 5 > Treatment of Acute Diarrhea With Saccharomyces boulardii in...
Journal of Pediatric Gastroenterology & Nutrition:
doi: 10.1097/MPG.0b013e31822b7ab0
Original Article: Gastroenterology

Treatment of Acute Diarrhea With Saccharomyces boulardii in Infants

Corrêa, Naflesia B.O.; Penna, Francisco J.*; Lima, Fátima M.L.S.; Nicoli, Jacques R.; Filho, Luciano A.P.*

Collapse Box

Abstract

Objective: The aim of the study was to determine whether an oral treatment with a commercial pharmaceutical product containing Saccharomyces boulardii would reduce the duration of diarrhea in infants with acute diarrhea.

Patients and Methods: In the present double-blind, placebo-controlled study, 186 infants, 6 to 48 months old and hospitalized within 72 hours after the onset of acute diarrhea in 2 hospitals in Goiânia, Goiás, Brazil, were randomly assigned to receive twice per day for 5 days 200 mg of a commercial pharmaceutical product containing 4 × 109 viable cells of S boulardii or a placebo. Stool samples were submitted to search for rotavirus. Among the 176 infants who completed the trial, those treated with S boulardii (90) showed a reduction in diarrhea duration (P < 0.05) when compared with the placebo group (86).

Results: The present study shows a reduction in diarrhea duration when S boulardii was given to children within 72 hours after the onset of acute diarrhea.

Conclusions: The present study suggests a complementary treatment of acute diarrhea in infants with daily oral doses of S boulardii.

Copyright 2011 by ESPGHAN and NASPGHAN

Login

Article Tools

Share

Article Level Metrics

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.

Connect With Us

 

 

Twitter

twitter.com/JPGNonline