Skip Navigation LinksHome > October 2011 - Volume 53 - Issue 4 > Zinc Monotherapy From Time of Diagnosis for Young Pediatric...
Journal of Pediatric Gastroenterology & Nutrition:
doi: 10.1097/MPG.0b013e31821d5abe
Short Communications

Zinc Monotherapy From Time of Diagnosis for Young Pediatric Patients With Presymptomatic Wilson Disease

Mizuochi, Tatsuki*; Kimura, Akihiko*; Shimizu, Norikazu; Nishiura, Hiroshi*; Matsushita, Masami*; Yoshino, Makoto*

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ABSTRACT: In 4 young pediatric patients with presymptomatic Wilson disease, we found zinc monotherapy beginning at time of diagnosis to be safe and highly effective for follow-up intervals between 1 and 2 years. Such maintenance therapy with zinc can maintain urinary copper excretion between 1 and 3 μg · kg−1 · day−1.

Copyright 2011 by ESPGHAN and NASPGHAN


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