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Esophageal pH Monitoring With the BRAVO Capsule: Experience in a Single Tertiary Medical Center

Cabrera, José; Davis, Miriam; Horn, Debbie; Pfefferkorn, Marian; Croffie, Joseph M.

Journal of Pediatric Gastroenterology & Nutrition:
doi: 10.1097/MPG.0b013e3182203caa
Original Articles: Gastroenterology
Abstract

Aim: The aim of the present study was to report the global experience with placement, complication rate, and recording of esophageal pH using the BRAVO capsule at our institution.

Patients and Methods: We recorded the rate of any technical problems and complications during placement in all of the patients (ages 4–22 years) who received this device during a 2-year period. All of the patients undergoing esophagogastroduodenoscopy with the placement of BRAVO pH capsule were included in this analysis. We also examined the pH data recorded on days 1 and 2 for significant day-to-day variability during 2 days of pH monitoring.

Results: Two hundred eighty-nine BRAVO pH probes were placed from January 1, 2006 to December 31, 2008. At least 1 day of data was obtained in 278 patients (96.2%). Two days of data were obtained in 274 patients (94.8%). Of all of the reported complications, 1% occurred before deployment of the capsule, 4% occurred during deployment of the capsule, and 9% occurred after successful deployment of the capsule. One patient experienced a superficial esophageal tear that was associated with failure of the capsule to release from the delivery system. No patient requested removal of the capsule and all of the capsules detached within 14 days. In 9.12% of our patients, reflux index was normal on day 1 and abnormal on day 2. There was no statistically significant difference between reflux index recorded on day 1 versus day 2 (P = 0.686).

Conclusions: The BRAVO pH capsule is easy to place, safe, and well tolerated by children. Performing a 48-hour study detected abnormal reflux in an additional 9% of our patients.

Author Information

Division of Pediatric Gastroenterology, Hepatology and Nutrition, Indiana University School of Medicine, Indianapolis, IN.

Address correspondence and reprint requests to Jose Cabrera, MD, 702 Barnhill Dr, ROC Room 4210, Indianapolis, IN 46202 (e-mail: jmcabrer@iupui.edu).

Received 23 November, 2010

Accepted 18 April, 2011

The authors report no conflicts of interest.

Copyright 2011 by ESPGHAN and NASPGHAN