ABSTRACT: The late adolescent linear growth pattern of pediatric patients with inflammatory bowel disease (IBD) has rarely been studied. We retrospectively reviewed the height measurements of 475 patients with IBD at 16, 18, and 20 years old for girls, and 18 and 20 years old for boys. We also compared Bayley-Pinneau bone age–predicted and –measured adult heights. Female patients had mean height-for-age z scores of −0.25 ± 1.0 at 16 years and −0.23 ± 1.0 at 18 years (P = 0.189); boys had z scores of −0.30 ± 1.1 at 18 years and −0.26 ± 1.0 at 20 years, respectively (P = 0.105). Bayley-Pinneau height predictions were 1.5 and 2.4 cm greater than measured height for 18-year-old girls (P = 0.060) and 20-year-old boys (P = 0.017), respectively. Our data indicate that most patients with IBD attain adult height within normal timing for the population. Hence, early identification of growth impairment is critical to appropriate management in IBD.
*Division of Gastroenterology and Nutrition, Children's Hospital Boston
†Division of Endocrinology, Children's Hospital Boston, Boston, MA.
Address correspondence and reprint requests to Jessica J. Lee, MD, MMSc, Division of Gastroenterology, Children's Hospital Boston, 300 Longwood Ave, Boston, MA 02115 (e-mail: Jessica.firstname.lastname@example.org).
Received 20 December, 2010
Accepted 3 March, 2011
The Crohn's and Colitis Foundation of America Career Development Award supported J.J.L. during the conduct of this study.
The authors report no conflicts of interest.