Ten Malawian children, ages 3 to 5 years, at risk for zinc deficiency and receiving a habitual maize-based high-phytate diet, received maize after phytate reduction for 40 days and had their endogenous fecal zinc (EFZ) measured using stable isotope techniques before and after phytate reduction. The phytate:Zn of the diet before reduction was 23.0 and afterward was 7.6. EFZ was similar before and after dietary phytate reduction, 1.15 ± 0.33 and 1.17 ± 0.16 mg/day, respectively. EFZ was not affected by dietary phytate in this population.
*Department of Pediatrics, Washington University School of Medicine, St Louis, USA
†University of Colorado, Denver, USA
‡College of Medicine, University of Malawi, Blantyre.
Received 4 February, 2010
Accepted 28 April, 2010
Address correspondence and reprint request to Dr Mark Manary, Department of Pediatrics, St Louis Children's Hospital, One Children's Place, St Louis, MO 63110 (e-mail: firstname.lastname@example.org).
The work was supported by the Allen Foundation.
The authors report no conflict of interest.