Enter your Email address:
Wolters Kluwer Health may email you for journal alerts and information, but is committed
to maintaining your privacy and will not share your personal information without
Stanford, E. J.
Gynecology, University of Tennessee, Memphis, TN
DISCLOSURE OF RELEVANT FINANCIAL RELATIONSHIPS: Edward Stanford:Ortho McNeil:Research grant:Researcher
To evaluate perceived response to treatment in patients diagnosed with interstitial cystitis (IC).
A retrospective database review and telephone survey was conducted at a reference Urogynecologic center. The records of 212 confirmed IC patients were identified of which 122 patients completed a telephone survey (58%) to confirm results. Of the 122 patients, 37 (30.3%) had a diagnosis of IC alone, 54 had one concomitant disorder (44.3%) and 31 had >one concomitant disorder (25.3%). Patients were given a list of treatments and were asked to rate which treatment was most effective in relieving their symptoms related to their chronic pelvic pain (CPP) and IC. IRB approval was obtained.
Treatments of interest were diet, pentosan polysulfate (PPS), intravesical heparin, or other (neuromodulation). Cystoscopy with hydrodistension and dimethyl sulfoxide (DMSO) were not offered to this patient cohort. Patients ranked PPS (29.6%), diet with PPS (23.5%), and intravesical heparin with PPS (15.7%) as most helpful in improving their symptoms related to the chronic pelvic pain and IC. Diet alone was judged as helpful in only 5.2%. Despite the fact that 85 patients (69.7%) had IC and concomitant disorders, surgery was not judged as particularly helpful compared to medical therapy in relieving chronic pain symptoms.
Patients with IC with or without concomitant disorders perceive medical therapy with PPS alone, PPS with diet modifications, and PPS with intravesical heparin as most helpful in relieving CPP/IC symptoms. Surgical therapies were judged as less helpful.
Interstitial cystitis; Treatment; Chronic pelvic pain; Heparin; Pentosan polysulfate
© 2010 by Wolters Kluwer Health | Lippincott Williams & Wilkins
Colleague's E-mail is Invalid
Your Name: (optional)
Separate multiple e-mails with a (;).
Thought you might appreciate this item(s) I saw at Female Pelvic Medicine & Reconstructive Surgery.
Send a copy to your email
Your message has been successfully sent to your colleague.
Some error has occurred while processing your request. Please try after some time.
An Existing Folder
A New Folder
The item(s) has been successfully added to "".
Login with your LWW Journals username and password.
Username or Email:
Enter and submit the email address you registered with. An email with instructions to reset your password will be sent to that address.
Link to reset your password has been sent to specified email address.
What does "Remember me" mean?
By checking this box, you'll stay logged in until you logout. You'll get easier access to your articles, collections,
media, and all your other content, even if you close your browser or shut down your
To protect your most sensitive data and activities (like changing your password),
we'll ask you to re-enter your password when you access these services.
What if I'm on a computer that I share with others?
If you're using a public computer or you share this computer with others, we recommend
that you uncheck the "Remember me" box.
Save my selection
Article Level Metrics
Highlight selected keywords in the article text.
Search for Similar Articles
You may search for similar articles that contain these same keywords or you may
modify the keyword list to augment your search.