Randomized Trial Comparing 2 Fiber Regimens for the Reduction of Symptoms of ConstipationHull, Margaret A. MSN; McIntire, Donald D. PhD; Atnip, Shanna D. MSN; Dreadin, Julie MSN; Nihira, Mikio A. MD; Drewes, Peter G. MD; Schaffer, Joseph I. MD; Wai, Clifford Y. MDFemale Pelvic Medicine & Reconstructive Surgery: May/June 2011 - Volume 17 - Issue 3 - pp 128-133 doi: 10.1097/SPV.0b013e31821a8b4d Original Articles Abstract In Brief Author Information Objective: This study aimed to compare the effects of a special bowel recipe with psyllium on symptoms of constipation. Methods: Women with symptoms of constipation were randomized to 6 weeks of either psyllium or a special bowel recipe. Patients completed a constipation scoring questionnaire and recorded characteristics of each bowel movement. Results: A total of 53 participants completed prestudy and poststudy constipation scoring questionnaires. Both groups demonstrated improvement in constipation scores (psyllium: 13.9 ± 4.7 to 9.0 ± 4.6, P < 0.001; recipe: 13.6 ± 4.1 to 8.5 ± 5.0, P < 0.001). Mean differences in pretreatment and posttreatment constipation scores were not statistically different between the 2 groups. Subjects taking the bowel recipe strained only 20% of the time compared with those using psyllium who strained 57% of the time (P = 0.007). Other symptoms improved from baseline, but the majority was not different between treatment groups. Conclusions: The bowel recipe demonstrated no significant difference in efficacy to pure fiber. A bowel recipe consisting of wheat bran, applesauce, and prune juice is an inexpensive and efficacious alternative to pure fiber for the treatment of constipation. From the Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX. Reprints: Clifford Y. Wai, MD, Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390-9032. E-mail: Clifford.Wai@UTSouthwestern.edu. Copyright © 2011 Wolters Kluwer Health, Inc. All rights reserved.