Journal of Trauma Nursing

Skip Navigation LinksHome > January/February 2014 - Volume 21 - Issue 1 > Predictors of Hypotension Associated With Propofol in Trauma...
Journal of Trauma Nursing:
doi: 10.1097/JTN.0000000000000022

Predictors of Hypotension Associated With Propofol in Trauma Patients

Shearin, Amanda E. PharmD; Patanwala, Asad E. PharmD; Tang, Andrew MD; Erstad, Brian L. PharmD

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Propofol use may lead to hypotension in trauma patients intubated in the emergency department. In this study, predictors of hypotension were identified. We hypothesized that demographic variables could be associated with hypotension. Hypotension occurred in 33 of 200 patients. In the multivariate analysis, hypotension was associated with patient age greater than 55 years (odds ratios [OR], 3.61; 95% confidence interval [CI], 1.32-9.86; P = .012), obesity (OR, 2.66; 95% CI, 1.08-6.55; P = .034), and lower baseline blood pressure (OR, 1.59 [per 10-mm Hg decrease]; 95% CI, 1.29-1.96; P = .000). Age greater than 55 years, obesity, and lower baseline systolic blood pressure are associated with a higher risk of propofol-induced hypotension in trauma patients.

Copyright © 2014 by the Society of Trauma Nurses.


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