Journal of Infusion Nursing

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Journal of Infusion Nursing:

Haploidentical Transplantation: Importance of Histocompatibility Testing and Chimerism Studies in Allogeneic Bone Marrow/Stem Cell Transplantation

Rebellato, Lorita M. PhD, Dip ABHI; Dobbs, Larry J. Jr MD, PhD

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The transplantation of hematopoietic stem cells is sometimes the only treatment option for certain types of malignancies and hematological disorders. The best way to ensure a positive outcome from this type of procedure is to secure an identical human lymphocyte antigen-matched donor or use an autologous graft. This article reviews the indications for transplantation, the recipient and donor selection process, and posttransplant follow-up. The advantages of using haploidentical donors and the typing process also will be discussed.

© Copyright 2001 by the Infusion Nurses Society


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