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Depression in Kidney Transplant Recipients: Prevalence, Risk Factors, and Association With Functional Disabilities

Srifuengfung, Maytinee MD*; Noppakun, Kajohnsak MD; Srisurapanont, Manit MD*

Journal of Nervous & Mental Disease: October 2017 - Volume 205 - Issue 10 - p 788–792
doi: 10.1097/NMD.0000000000000722
Original Articles

Abstract: This study examined the prevalence, risk factors, and disability associated with depression. We conducted a cross-sectional, observational study in 217 consecutive kidney transplant (KT) recipients routinely followed-up at a Kidney Transplantation Clinic in Northern Thailand. Participants were assessed using the Charlson Comorbidity Index (CCI), the nine-item Patient Health Questionnaire (PHQ-9), and the 12-item self-report of World Health Organization Disability Assessment Scale, Version 2.0 (WHODAS). Twenty-eight (12.9%) patients had depression (PHQ-9 score, ≥10). A binary logistic regression analysis found that the CCI score was significantly higher in KT recipients with depression (β = 0.54, p < 0.01). After the adjustment of education and glomerular filter rates, an ordinal logistic regression analysis revealed that the PHQ-9 scores were positively correlated with the WHODAS scores (β = 0.39, p < 0.01). In KT recipients, physical comorbidity is associated with depression, and depression is correlated with functional disability.

*Department of Psychiatry, and †Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

Send reprint requests to Manit Srisurapanont, MD, Department of Psychiatry, Faculty of Medicine, Chiang Mai University, 110 Intavaroros Road, Si Poom, Muang, Chiang Mai 50200, Thailand. E-mail: manit.s@cmu.ac.th.

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