Skip Navigation LinksHome > August 2014 - Volume 202 - Issue 8 > Selective Effect of Neurocognition on Different Theory of Mi...
Journal of Nervous & Mental Disease:
doi: 10.1097/NMD.0000000000000164
Original Articles

Selective Effect of Neurocognition on Different Theory of Mind Domains in First-Episode Psychosis

Fernandez-Gonzalo, Sol MD*†; Jodar, Merce PhD†‡; Pousa, Esther PhD†§; Turon, Marc MD*†; Garcia, Rebeca MD§; Rambla, Carla Hernandez MD§; Palao, Diego PhD§∥

Collapse Box

Abstract

The aim of this study was to investigate the influence of neurocognition on affective and cognitive theory of mind (ToM) tasks in early phases of psychosis. In a cross-sectional study of 60 first-episode schizophrenia/schizoaffective disorder patients, the implication of neurocognition in first- and second-order ToM stories, Hinting Task, and Reading the Mind in the Eyes Test (RMET) was analyzed. Regression models were used, controlling for clinical symptoms and antipsychotic dose. Spatial span backward (odds ratio [OR], 0.34; p = 0.01) and intrusions in the Rey Auditory Verbal Learning Test (OR, 4.86; p = 0.04) were the best factors to predict second-order ToM failure. Trail Making Test B (B = 0.01; p = 0.04) and negative symptoms (B = 0.09; p = 0.01) predicted Hinting task performance while Block design (B = 0.1; p = 0.04) was related to RMET outcome. Executive functions and clinical symptoms were related to ToM performance in first-episode schizophrenia patients, although different patterns of relationship were observed in each ToM task.

Copyright © 2014 by Lippincott Williams & Wilkins

Login

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.