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Occupational Exposures and Metabolic Syndrome Among Hispanics/Latinos: Cross-Sectional Results From the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

Bulka, Catherine M. MPH; Daviglus, Martha L. MD, PhD; Persky, Victoria W. MD; Durazo-Arvizu, Ramon A. PhD; Avilés-Santa, M. Larissa MD, MPH; Gallo, Linda C. PhD; Hosgood, H. Dean III PhD, MPH; Singer, Richard H. DMD, MS; Talavera, Gregory A. MD, MPH; Thyagarajan, Bharat MD, PhD, MPH; Zeng, Donglin PhD; Argos, Maria PhD

Journal of Occupational and Environmental Medicine: November 2017 - Volume 59 - Issue 11 - p 1047–1055
doi: 10.1097/JOM.0000000000001115
Original Articles

Objective: We assessed the cross-sectional relationships of self-reported current occupational exposures to solvents, metals, and pesticides with metabolic syndrome and its components among 7127 participants in the Hispanic Community Health Study/Study of Latinos.

Methods: Metabolic syndrome was defined as a clustering of abdominal obesity, high triglycerides, low high-density lipoprotein cholesterol, high blood pressure, and/or high fasting glucose. Regression models that incorporated inverse probability of exposure weighting were used to estimate prevalence ratios.

Results: Solvent exposure was associated with a 32% higher prevalence of high blood pressure (95% confidence interval: 1.09 to 1.60) than participants not reporting exposure. No associations were observed for occupational exposures with abdominal obesity, high triglycerides, low high-density lipoprotein, or metabolic syndrome.

Conclusion: Our findings suggest that solvent exposure may be an important occupational risk factor for high blood pressure among Hispanics/Latinos in the United States.

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Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, Illinois (Ms Bulka, Drs Persky, Argos); Institute for Minority Health Research, Section of General Internal Medicine, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois (Ms Bulka, Drs Daviglus, Durazo-Arvizu); National Heart, Lung, and Blood Institute at the National Institutes of Health, Bethesda, Maryland (Dr Avilés-Santa); Department of Psychology, San Diego State University, San Diego, California (Dr Gallo); Department of Epidemiology and Population Health, Albert Einstein College of Medicine, New York City, New York (Dr Hosgood III); Department of Public Health Sciences, University of Miami Miller School of Medicine, Miami, Florida (Dr Singer); Division of Health Promotion and Behavioral Science, San Diego State University, San Diego, California (Dr Talavera); Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota (Dr Thyagarajan); and Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (Dr Zeng).

Address correspondence to: Maria Argos, PhD, University of Illinois at Chicago, 1603 W. Taylor Street, MC 923, Chicago, IL 60612. (

Catherine Bulka was supported by the National Heart, Lung, and Blood Institute (NHLBI) T32-HL125294. The Hispanic Community Health Study/Study of Latinos was carried out as a collaborative study supported by contracts from the NHLBI to the University of North Carolina (N01-HC65233), University of Miami (N01-HC65234), Albert Einstein College of Medicine (N01-HC65235), University of Illinois at Chicago (HHSN268201300003I), Northwestern University (N01-HC65236), and San Diego State University (N01-HC65237). The following Institutes/Centers/Offices contribute to the HCHS/SOL through a transfer of funds to the NHLBI: National Institute on Minority Health and Health Disparities, National Institute on Deafness and Other Communication Disorders, National Institute of Dental and Craniofacial Research, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Neurological Disorders and Stroke, NIH Institution-Office of Dietary Supplements. The views expressed in this manuscript are those of the authors and do not necessarily represent the views of the National Heart, Lung, and Blood Institute; the National Institutes of Health; or the U.S. Department of Health and Human Services.

The authors have no conflicts of interest.

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Copyright © 2017 by the American College of Occupational and Environmental Medicine