Skip Navigation LinksHome > August 2014 - Volume 56 - Issue 8 > Health Care Worker Exposures to the Antibacterial Agent Tric...
Journal of Occupational & Environmental Medicine:
doi: 10.1097/JOM.0000000000000183
Original Articles

Health Care Worker Exposures to the Antibacterial Agent Triclosan

MacIsaac, Julia K. MD, MPH; Gerona, Roy R. PhD; Blanc, Paul D. MD, MSPH; Apatira, Latifat MD, MPH; Friesen, Matthew W.; Coppolino, Michael MD; Janssen, Sarah MD, PhD, MPH

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Objective: We sought to quantify absorption of triclosan, a potential endocrine disruptor, in health care workers with occupational exposure to soap containing this chemical.

Methods: A cross-sectional convenience sample of two groups of 38 health care workers at separate inpatient medical centers: hospital 1 uses 0.3% triclosan soap in all patient care areas; hospital 2 does not use triclosan-containing products. Additional exposure to triclosan-containing personal care products was assessed through a structured questionnaire. Urine triclosan was quantified and the occupational contribution estimated through regression modeling.

Results: Occupational exposure accounted for an incremental triclosan burden of 206 ng/mL (P = 0.02), while triclosan-containing toothpaste use was associated with 146 ng/mL higher levels (P < 0.001).

Conclusions: Use of triclosan-containing antibacterial soaps in health care settings represents a substantial and potentially biologically relevant source of occupational triclosan exposure.

Copyright © 2014 by the American College of Occupational and Environmental Medicine


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