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Journal of Occupational & Environmental Medicine:
doi: 10.1097/JOM.0b013e318298fae4
Original Articles

Occupation and Head and Neck Cancer Risk in Men: Results From the ICARE Study, a French Population-Based Case–Control Study

Paget-Bailly, Sophie PhD; Guida, Florence PharmD, PhD; Carton, Matthieu MD; Menvielle, Gwenn PhD; Radoï, Loredana DDS, PhD; Cyr, Diane MS; Schmaus, Annie MS; Cénée, Sylvie MS; Papadopoulos, Alexandra PhD; Févotte, Joëlle MS; Pilorget, Corinne PhD; Velten, Michel MD; Guizard, Anne-Valérie MD; Stücker, Isabelle PhD; Luce, Danièle PhD

Supplemental Author Material
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Abstract

Objective: To investigate the associations between occupations and head and neck (HN) cancer risk in men.

Methods: ICARE is a French population-based case–control study on HN cancer. Analyses included 1833 cases and 2747 controls. Complete occupational history was collected. Odds ratios (ORs) were estimated for occupations and industries ever held and according to duration of employment.

Results: Elevated ORs, increasing with duration of employment, were observed for several occupations, including cleaners (OR = 1.7; 95% confidence interval [CI], 1.0 to 2.8), launderers (OR = 6.8; CI, 1.3 to 34.4), firefighters (OR = 3.9; CI, 1.4 to 11.2), several agricultural occupations, welders (OR = 1.9; CI, 1.3 to 2.8), structural metal preparers and erectors (OR = 2.1; CI, 1.2 to 3.7), rubber workers (OR = 2.0; CI, 1.0 to 3.9), several construction occupations, and material-handling equipment operators (OR = 1.8; CI, 1.1 to 2.9). Analyses by industry corroborated these findings.

Conclusions: These results confirmed the role of occupational exposures in HN cancer.

Copyright © 2013 by the American College of Occupational and Environmental Medicine

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