Objective: Because of its high prevalence, early screening for occupational asthma (OA) is crucial. We aimed to evaluate the screening performance of the Occupational Asthma Screening Questionnaire–11 items (OASQ-11) in a clinical setting.
Methods: Between January 2009 and December 2011, 169 workers referred for potential OA to our hospital completed the OASQ-11 and underwent workups to determine the final diagnosis. The discriminative abilities of the OASQ-11 as a whole and in relation to demographic and exposure parameters were determined by the area under the receiving operator characteristic curve (AUC).
Results: Model 1, consisting of the OASQ's items, showed fair discrimination (AUC, 0.69; 95% confidence interval, 0.58 to 0.80). Addition of age and exposure duration to model 1 improved discrimination (AUC, 0.80; confidence interval, 0.72 to 0.88).
Conclusion: A simple model consisting of the OASQ-11's items, age, and exposure duration could well discriminate subjects with OA in a clinical setting.
From the Research Center (Drs Pralong, Moullec, Suarthana, Gautrin, L' Archevêque, and Labrecque), Hôpital du Sacré-Coeur de Montréal, and Department of Environmental and Occupational Health (Dr Gérin), Université de Montréal, Montreal, Quebec, Canada; and Institute for Work and Health (Dr Pralong), University of Lausanne and Geneva, Lausanne, Switzerland.
Address correspondence to: Jacques A. Pralong, MD, MSc, Institute for Work and Health, University of Lausanne and Geneva, Rue du Bugnon 21, 1011 Lausanne, Switzerland (Jacques.Pralong@chuv.ch).
The authors declare no conflicts of interest.
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