Because of its high prevalence, early screening for occupational asthma (OA) is crucial. We aimed to evaluate the screening performance of the Occupational Asthma Screening Questionnaire–11 items (OASQ-11) in a clinical setting.
Between January 2009 and December 2011, 169 workers referred for potential OA to our hospital completed the OASQ-11 and underwent workups to determine the final diagnosis. The discriminative abilities of the OASQ-11 as a whole and in relation to demographic and exposure parameters were determined by the area under the receiving operator characteristic curve (AUC).
Model 1, consisting of the OASQ's items, showed fair discrimination (AUC, 0.69; 95% confidence interval, 0.58 to 0.80). Addition of age and exposure duration to model 1 improved discrimination (AUC, 0.80; confidence interval, 0.72 to 0.88).
A simple model consisting of the OASQ-11's items, age, and exposure duration could well discriminate subjects with OA in a clinical setting.
From the Research Center (Drs Pralong, Moullec, Suarthana, Gautrin, L' Archevêque, and Labrecque), Hôpital du Sacré-Coeur de Montréal, and Department of Environmental and Occupational Health (Dr Gérin), Université de Montréal, Montreal, Quebec, Canada; and Institute for Work and Health (Dr Pralong), University of Lausanne and Geneva, Lausanne, Switzerland.
Address correspondence to: Jacques A. Pralong, MD, MSc, Institute for Work and Health, University of Lausanne and Geneva, Rue du Bugnon 21, 1011 Lausanne, Switzerland (Jacques.Pralong@chuv.ch).
The authors declare no conflicts of interest.
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