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Journal of Occupational & Environmental Medicine:
doi: 10.1097/JOM.0b013e318255ba74
Original Articles

Characterization of Frequency-Dependent Responses of the Vascular System to Repetitive Vibration

Krajnak, Kristine PhD; Miller, G. Roger BS; Waugh, Stacey MS; Johnson, Claud BS; Kashon, Michael L. PhD



The title of this paper in a recent issue of JOEM was published in error. The correct title is “Frequency-Dependent Effects of Vibration on Peripheral Nerves and Sensory Nerve Function in a Rat Model of Hand-Arm Vibration Syndrome.” The editors regret the error.

Journal of Occupational and Environmental Medicine. 54(11):1431, November 2012.

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Objective: Occupational exposure to hand-transmitted vibration can result in damage to nerves and sensory loss. The goal of this study was to assess the frequency-dependent effects of repeated bouts of vibration on sensory nerve function and associated changes in nerves.

Methods: The tails of rats were exposed to vibration at 62.5, 125, or 250 Hz (constant acceleration of 49 m/s2) for 10 days. The effects on sensory nerve function, nerve morphology, and transcript expression in ventral tail nerves were measured.

Results: Vibration at all frequencies had effects on nerve function and physiology. However, the effects tended to be more prominent with exposure at 250 Hz.

Conclusion: Exposure to vibration has detrimental effects on sensory nerve function and physiology. However, many of these changes are more prominent at 250-Hz exposure than at lower frequencies.

©2012The American College of Occupational and Environmental Medicine


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