Skip Navigation LinksHome > July 2012 - Volume 54 - Issue 7 > Screening Health Care Workers With Interferon-γ Release Assa...
Journal of Occupational & Environmental Medicine:
doi: 10.1097/JOM.0b013e318254620f
Original Articles: CME Available for this Article at

Screening Health Care Workers With Interferon-γ Release Assay Versus Tuberculin Skin Test: Impact on Costs and Adherence to Testing (the SWITCH study)

Wrighton-Smith, Peter MEng, PhD; Sneed, Laurie AA; Humphrey, Frances MSN; Tao, Xuguang MD, PhD; Bernacki, Edward MD, MPH

Supplemental Author Material
Continued Medical Education
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Objective: To determine the price point at which an interferon-γ release assay (IGRA) is less costly than a tuberculin skin test (TST) for health care employee tuberculosis screening.

Methods: A multidecision-tree based cost model incorporating inputs gathered from time–motion studies and parallel testing by IGRA and TST was conducted in a subset of our employees.

Results: Administering a TST testing program costs $73.20 per person screened, $90.80 per new hire, and $63.42 per annual screen. Use of an IGRA for employee health testing is cost saving at an IGRA test cost of $54.83 or less per test and results in higher completion rates because of the elimination of the need for a second visit to interpret the TST.

Conclusions: Using an IGRA for employee health screening can be an institutional cost saving and results in higher compliance rates.

©2012The American College of Occupational and Environmental Medicine


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