Objective: To determine whether job-related stress is associated with alterations in pro- and anti-atherogenic inflammatory mediators among law enforcement officers.
Methods: Markers of vascular inflammation and the self-reported stress measures of perceived stress, vital exhaustion, job strain, effort-reward imbalance, and social support were compared between officers (N = 444) and non-officers (N = 166).
Results: Officers had higher levels of IL-1β, IL-6, IL-10, and TNF-α and lower levels of C-reactive protein and fibrinogen. No more than 4% of the variability in any of the inflammatory mediators was explained by any stress measure for either the two groups or the entire sample.
Conclusions: Law enforcement officers may be at an increased risk for cardiovascular disease due to a relatively greater pro-inflammatory vascular environment. However, this increased risk cannot be attributed to either chronic stress or the work-related stress measures assessed here.
From the Department of Kinesiology (Dr Franke, Dr Kohut, Ms Yoo, Dr Ekkekakis); Department of Human Development and Family Studies (Dr Russell), Institute for Social and Behavioral Research, Iowa State University, Ames, Iowa; and College of Nursing (Dr Ramey), University of Iowa, Iowa City, Iowa.
Address correspondence to: Warren D. Franke, PhD, 247 Forker Building, Ames, IA 50011; E-mail: firstname.lastname@example.org.