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Journal of Occupational & Environmental Medicine:
doi: 10.1097/JOM.0b013e3181cb59bc
Original Articles

Reproductive Outcomes Among Male and Female Workers at an Aluminum Smelter.

Sakr, Carine J. MD, MPH; Taiwo, Oyebode A. MD, MPH; Galusha, Deron H. MS; Slade, Martin D. MPH; Fiellin, Martha G. MPH; Bayer, Felicia MSN, RN-C; Savitz, David A. PhD; Cullen, Mark R. MD

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Abstract

Objectives: Several adverse pregnancy outcomes were reported among female laboratory workers in a North American aluminum smelter. To determine whether these outcomes were associated with any occupational exposure at the plant, a cross-sectional survey was undertaken.

Methods: Rates of miscarriage, premature singleton birth, and major congenital anomaly occurring during employment were compared with a reference group comprised of all pregnancies that occurred before employment.

Results: Among female workers, the excess of congenital anomalies among female laboratory workers that defined the initial cluster was observed, but no specific pattern was found.

Conclusions: On the basis of these analyses, the increase in congenital anomalies could not be attributed to occupational exposures at the smelter nor could potential exposure likely explain the diverse anomalies described.

©2010The American College of Occupational and Environmental Medicine

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