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Journal of Occupational & Environmental Medicine:
doi: 10.1097/JOM.0b013e3181cd7e80
Original Articles

Evaluation of Coumaphos Exposure Among Tick Eradication Workers.

Thomas, Gregory A. MD, MS; Delaney, Lisa J. MS, CIH; Mueller, Charles MS; Page, Elena MD, MPH

Continued Medical Education
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Abstract

Objective: To evaluate both the cholinesterase monitoring program and newer field methods of determining coumaphos exposure among tick eradication workers.

Methods: Measured blood cholinesterase by the Ellman and field testing methods and tested urine for chlorferon pre- and postshift; conducted personal air sampling, patch sampling of clothing, and wipe sampling of hands for coumaphos.

Results: Fifteen workers had normal plasma cholinesterase and acetylcholinesterase levels. No significant changes occurred pre- to postshift. High correlation was found between plasma cholinesterase and acetylcholinesterase levels by field testing and Ellman methods (r = 0.91, P < 0.01 and r = 0.63, P < 0.01, respectively). Chlorferon levels rose 4 to 6 hours after use (P < 0.01). Airborne coumaphos was detected in only one sample, in a trace amount. The majority of patch and hand wipe samples detected coumaphos.

Conclusions: Dermal exposure to coumaphos resulted in significant increases in urinary metabolites of coumaphos.

©2010The American College of Occupational and Environmental Medicine

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