Skip Navigation LinksHome > July 2009 - Volume 51 - Issue 7 > The Idiopathic Environmental Intolerance Symptom Inventory:...
Journal of Occupational & Environmental Medicine:
doi: 10.1097/JOM.0b013e3181a7f021
Original Articles

The Idiopathic Environmental Intolerance Symptom Inventory: Development, Evaluation, and Application

Andersson, Maria J. E. MSc; Andersson, Linus MSc; Bende, Mats MD, PhD; Millqvist, Eva MD, PhD; Nordin, Steven PhD

Collapse Box


Objective: To develop, evaluate, and apply a questionnaire-based instrument for investigation of specific symptoms in idiopathic environmental intolerance (IEI), called the Idiopathic Environmental Intolerance Symptom Inventory (IEISI).

Methods: Participants with IEI to chemicals responded to 82 candidate symptoms and to three subscales of the Quick Environmental Exposure and Sensitivity Inventory (QEESI) at a test (n = 207) and retest (n = 193) occasion.

Results: The 27 most commonly reported symptoms were selected and grouped into five symptom categories. Internal consistency, test–retest reliability, and concurrent validity were found to be satisfying. Cluster analysis identified two subgroups of IEI to chemicals.

Conclusions: The results provide support for the IEISI being a reliable, valid, and fast tool for the study of specific symptom prevalence in IEI and encourage further study of subgroups.

©2009The American College of Occupational and Environmental Medicine


Article Tools


Article Level Metrics