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Journal of Occupational & Environmental Medicine:
doi: 10.1097/JOM.0b013e3181895e10
Original Articles

Impaired Work Performance Among Women With Symptomatic Uterine Fibroids

Lerner, Debra MS, PhD; Mirza, Fadi MD; Chang, Hong PhD; Renzulli, Karen PsyD; Perch, Katherine BA; Chelmow, David MD

Continued Medical Education


In the article that appeared on page 1149 of the October 2008 issue, an author's middle initial was omitted. The author's full name is Fadi G. Mirza, MD.

Journal of Occupational and Environmental Medicine. 52(10):e1, October 2010.

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Objective: To assess the work impact of symptomatic uterine fibroids (UFs).

Methods: A cohort study compared 58 employed women with symptomatic UFs to 56 healthy controls. Data sources included a self-administered mail questionnaire and medical charts. At-work performance limitations and productivity loss were measured with the Work Limitations Questionnaire. Univariate and multivariate case-control group differences were tested.

Results: Based on adjusted mean scores, the UF group had significantly more at-work limitations and productivity loss than controls, while absence rates were similar. The UF group’s performance was impaired 18% of the time on average versus 8% for controls (P-values, 0.005–0.040). At-work limitations were explained by depression symptoms, Non-White race/ethnicity, and poorer health-related quality of life.

Conclusions: Fibroids and related symptoms impose a burden on the working lives’ of women, their employers, and the economy.

©2008The American College of Occupational and Environmental Medicine


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