Institutional members access full text with Ovid®

Association Between Betelnut Chewing and Chronic Kidney Disease in Adults

Kang, I-Min MD; Chou, Che-Yi MD; Tseng, Yu-Hsiung MD; Huang, Chiu-Ching MD; Ho, Wen-Yu; Shih, Chuen-Ming MD; Chen, Walter MD

Journal of Occupational & Environmental Medicine: July 2007 - Volume 49 - Issue 7 - pp 776-779
doi: 10.1097/JOM.0b013e318095a48a
Original Articles

Objective: This study was conduced to access the association between betelnut chewing and chronic kidney disease (CKD) in adults.

Methods: We retrospectively reviewed 3552 participants (1418 men and 2134 women) younger than 65 in this hospital-based cross-sectional study from 2003 to 2006.

Results: A total of 198 (5.6%) participants were found to have CKD and 287 (8.1%) participants (268 male and 19 female) reported a history of betelnut use. The prevalence (9.4%) of CKD in betelnut users was significantly higher than that (5.2%) of participants without betelnut use (P = 0.003). In multivariate logistic regression with adjustment for age, sex, hypertension, and diabetes, betelnut use and body mass index were independently associated with CKD (P = 0.026 and P = 0.038).

Conclusions: Betelnut use is associated with chronic kidney disease in adults younger than 65.

From the Department of Family Medicine (Drs Kang, Shih, and Chen), China Medical University Beigang Hospital, Yunlin, Taiwan; Division of Nephrology (Drs Chou and Tseng), Department of Internal Medicine, China Medical University Beigang Hospital, YunLin, Taiwan; Division of Nephrology (Dr Huang), Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan; Department of Laboratory Medicine (Ho), China Medical University Beigang Hospital, YunLin, Taiwan.

Address correspondence to: Che-Yi Chou MD, Division of Nephrology Department of Internal Medicine, China Medical University Beigang Hospital, No.123, Sinde Rd., Beigang Township, Yunlin County 65152, Taiwan; E-mail: cychou.chou@gmail.com.

©2007The American College of Occupational and Environmental Medicine