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Journal of Occupational & Environmental Medicine:
doi: 10.1097/JOM.0b013e318095a48a
Original Articles

Association Between Betelnut Chewing and Chronic Kidney Disease in Adults

Kang, I-Min MD; Chou, Che-Yi MD; Tseng, Yu-Hsiung MD; Huang, Chiu-Ching MD; Ho, Wen-Yu; Shih, Chuen-Ming MD; Chen, Walter MD

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Objective: This study was conduced to access the association between betelnut chewing and chronic kidney disease (CKD) in adults.

Methods: We retrospectively reviewed 3552 participants (1418 men and 2134 women) younger than 65 in this hospital-based cross-sectional study from 2003 to 2006.

Results: A total of 198 (5.6%) participants were found to have CKD and 287 (8.1%) participants (268 male and 19 female) reported a history of betelnut use. The prevalence (9.4%) of CKD in betelnut users was significantly higher than that (5.2%) of participants without betelnut use (P = 0.003). In multivariate logistic regression with adjustment for age, sex, hypertension, and diabetes, betelnut use and body mass index were independently associated with CKD (P = 0.026 and P = 0.038).

Conclusions: Betelnut use is associated with chronic kidney disease in adults younger than 65.

©2007The American College of Occupational and Environmental Medicine


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