Objective: This study was conduced to access the association between betelnut chewing and chronic kidney disease (CKD) in adults.
Methods: We retrospectively reviewed 3552 participants (1418 men and 2134 women) younger than 65 in this hospital-based cross-sectional study from 2003 to 2006.
Results: A total of 198 (5.6%) participants were found to have CKD and 287 (8.1%) participants (268 male and 19 female) reported a history of betelnut use. The prevalence (9.4%) of CKD in betelnut users was significantly higher than that (5.2%) of participants without betelnut use (P = 0.003). In multivariate logistic regression with adjustment for age, sex, hypertension, and diabetes, betelnut use and body mass index were independently associated with CKD (P = 0.026 and P = 0.038).
Conclusions: Betelnut use is associated with chronic kidney disease in adults younger than 65.