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Journal of Occupational & Environmental Medicine:
doi: 10.1097/01.jom.0000237773.26755.78
Original Articles

A Projection of the Impact of Lipid-Lowering Therapy on High-Risk Employee Disability and Medical Costs

Song, Xue PhD; Huse, Daniel M. MA; Williams, Setareh A. PhD; Borok, Gerald M. PhD; McDonough, Ken MD; Ozminkowski, Ronald J. PhD

Continued Medical Education
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Objective: The objective of this study was to examine the impact of introducing rosuvastatin calcium on direct and indirect costs among patients at high risk for coronary heart disease.

Methods: An economic simulation model was developed to project the number of cardiovascular events and associated direct and indirect costs under varying treatment scenarios.

Results: In an average-sized commercial health plan with 210,000 covered lives and 9,336 high-risk patients, an uptake of rosuvastatin by 11% of high-risk patients would result in eight fewer cardiovascular events, a net savings of $0.85 million in direct medical costs and a net savings of $36,404 in productivity loss over a period of 5 years. The overall reduction in total costs is equivalent to $1735 per rosuvastatin-treated patient.

Conclusions: At current statin prices, the use of rosuvastatin could lead to fewer cardiovascular events and lower direct and indirect costs.

©2006The American College of Occupational and Environmental Medicine


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