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Cancer Mortality in a Chinese Population Exposed to Hexavalent Chromium in Water

Zhang, JinDong MD; Li, ShuKun MD

Journal of Occupational & Environmental Medicine: April 1997 - Volume 39 - Issue 4 - pp 315-319
Original Article

This report is a clarification and further analysis of our previously published mortality study regarding groundwater contamination with hexavalent chromium (Cr+6) in the JinZhou area of China between 1965 and 1978. In our previous report, we stated that a significant excess of overall cancer mortality was observed (P = 0.04) in five Cr+6-contaminated villages combined. Further analysis revealed no clear statistical increase in cancer mortality in the three villages adjacent to the source of the contamination (P = 0.25), where 57% of the wells exceeded the European Community safe drinking water standard of 0.05 ppm Cr+6. These results do not indicate an association of cancer mortality with exposure to Cr+6-contaminated groundwater, but might reflect the influence of lifestyle or environmental factors not related to Cr+6. Further follow-up of this cohort is recommended.

From the JinZhou Health and Anti-Epidemic Station, JinZhou City (Dr Zhang), and the BenXi Health and Anti-Epidemic Station, BenXi City (Dr Li), Liao-Ning Province, China.

Address correspondence to: JinDong Zhang, MD, Renmin Street, Section 3, #12-15 Guta District, JinZhou City, Liao-Ning, People's Republic of China 121004

© Williams & Wilkins 1997. All Rights Reserved.