Skip Navigation LinksHome > November 1995 - Volume 37 - Issue 11 > A Case-Control Study of Leukemia Among Petroleum Workers.
Journal of Occupational & Environmental Medicine:
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A Case-Control Study of Leukemia Among Petroleum Workers.

Sathiakumar, Nalini MD; Delzell, Elizabeth SD; Cole, Philip MD; Brill, Ilene MPH; Frisch, Jonathan PhD; Spivey, Gary MD

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Abstract

This case-control study evaluates the relationship between leukemia and the work histories of active and retired employees of a large petroleum company. The study includes 69 cases with leukemia and 284 matched controls. Employment in production-related work in the oil and gas division was associated with myelogenous leukemia (odds ratio [OR]=2.0, 95% confidence interval [CI]=.97 to 4.2) and particularly with acute myelogenous leukemia (OR=2.8, 95% CI=1.1 to 7.3). The association with acute myelogenous leukemia was strongest for subjects in the highest tertile (32+ years) of duration of employment in oil- and gas production-related work (OR=8.7, 95 % CI=2.0 to 37), and there was a consistent trend of increasing ORs with increasing duration of employment (P= .01). No clear association was observed for refining division work and leukemia. This is the first epidemiologic study reporting a positive association between oil and gas field work and acute myelogenous leukemia.

(C)1995The American College of Occupational and Environmental Medicine

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