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Symptom Clusters in Women With Relapsing-Remitting Multiple Sclerosis

Newland, Pamela K.; Fearing, Arleen; Riley, Marguerite; Neath, Andrew

Journal of Neuroscience Nursing: April 2012 - Volume 44 - Issue 2 - p 66–71
doi: 10.1097/JNN.0b013e3182478cba
Article

ABSTRACT: The purpose of this secondary analysis was to investigate the relationships among a set of symptoms (fatigue, depression, impaired cognitive function, sleep disturbance) with pain severity and demographic variables. The sample of 40 women with relapsing-remitting multiple sclerosis completed instruments of pain, fatigue, depression, sleep disturbance, and an objective cognitive measure. Analysis identified one symptom cluster of pain, fatigue, depression, sleep disturbance, and impaired cognitive function, whereas a relationship between that symptom cluster and employment status existed. Pain severity correlated with fatigue, sleep disturbance, depression, and impaired cognitive function. Preliminary findings support providing education on symptoms to women with relapsing-remitting multiple sclerosis to ultimately guide their care.

Questions or comments about this article may be directed to Pamela K. Newland, RN PhD CMSRN, at pnewlan@siue.edu. She is a Ruth L. Kirschstein National Research Service Awards (NRSA) Postdoctoral Fellow and an assistant professor at the School of Nursing, Southern Illinois University Edwardsville, Edwardsville, IL.

Arleen Fearing, RN EdD CNE, is an associate professor emerita at the School of Nursing, Southern Illinois University Edwardsville, Edwardsville, IL.

Marguerite Riley, RN PhD CMSRN CNE, is an associate professor at the School of Nursing, Southern Illinois University Edwardsville, Edwardsville, IL.

Andrew Neath, PhD, is a professor at the Department of Mathematics and Statistics, Southern Illinois University Edwardsville, Edwardsville, IL.

This study was supported in part by a grant from Southern Illinois University Edwardsville.

The authors declare no conflicts of interest.

© 2012 American Association of Neuroscience Nurses