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Idiopathic Intracranial Hypertension Progressing to Venous Sinus Thrombosis, Subarachnoid Hemorrhage, and Stroke

Hardin Joshua S. MD; Ramakrishnaiah, Raghu H. MD; Pemberton, John D. MD; Phillips, Paul H. MD; Chacko, Joseph G. MD
Journal of Neuro-Ophthalmology: Post Author Corrections: July 24, 2017
doi: 10.1097/WNO.0000000000000540
Clinical Observation: PDF Only


Idiopathic intracranial hypertension (IIH) is a syndrome characterized by increased intracranial pressure (ICP), the absence of structural lesions on neuroimaging, and normal cerebrospinal fluid composition. Cerebral venous sinus thrombosis (CVST) is a common cause of increased ICP and can be differentiated from IIH with magnetic resonance venography. We describe a young woman with typical IIH who underwent lumbar puncture and was treated with a short course of high-dose corticosteroids followed by acetazolamide. She subsequently developed CVST, subarachnoid hemorrhage, and stroke. Risk factors that may have resulted in CVST are discussed.

Address correspondence to Paul H. Phillips, MD, Arkansas Children's Hospital, 1 Children's Way, Slot 111, Little Rock, AR 72202; E-mail:

The authors report no conflicts of interest.

© 2017 by North American Neuro-Ophthalmology Society