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Shedding Light on Photophobia

Digre, Kathleen B. MD; Brennan, K.C. MD

Section Editor(s): Liu, Grant T. MD; Kardon, Randy H. MD, PhD

Journal of Neuro-Ophthalmology: March 2012 - Volume 32 - Issue 1 - p 68–81
doi: 10.1097/WNO.0b013e3182474548
State-of-the-Art Review
Japanese Abstract

Photophobia is a common yet debilitating symptom seen in many ophthalmic and neurologic disorders. Despite its prevalence, it is poorly understood and difficult to treat. However, the past few years have seen significant advances in our understanding of this symptom. We review the clinical characteristics and disorders associated with photophobia, discuss the anatomy and physiology of this phenomenon, and conclude with a practical approach to diagnosis and treatment.

Departments of Ophthalmology (KBD) and Neurology (KBD, KCB), University of Utah, Salt Lake City, Utah.

Address correspondence to: Kathleen B. Digre, MD, Departments of Ophthalmology and Neurology, University of Utah, 65 Mario Capecchi Drive, Salt Lake City, UT 84132; E-mail:; K.C. Brennan, MD, Department of Neurology, University of Utah, 383 Colorow Drive, Salt Lake City, UT 84108; E-mail:

K. B. Digre was supported in part by an unrestricted grant from the Research to Prevent Blindness, Inc, New York, New York, to the Department of Ophthalmology and Visual Sciences, University of Utah. K.C. Brennan was supported by the National Institutes of Health (NS059072, NS070084) and the National Headache Foundation.

The authors report no conflicts of interest.

© 2012 Lippincott Williams & Wilkins, Inc.