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Misdiagnosis of an Extragastrointestinal Stromal Tumor in the Rectovaginal Septum

Meléndez, Marcos N. MD; Revello, Rocio MD; Cuerva, Marcos J. MD; De Santiago, Javier MD, PhD; Zapardiel, Ignacio MD, PhD

Journal of Lower Genital Tract Disease:
doi: 10.1097/LGT.0b013e3182a72156
Case Reports
Abstract

Introduction: Gastrointestinal stromal tumors are very rare, representing 0.1% to 1% of gastrointestinal malignancies. Gastrointestinal stromal tumors outside the digestive tract comprise a very small fraction of all gastrointestinal stromal tumors, and their most common locations are the omentum, the mesentery, and, in few cases, the rectovaginal septum. Despite their low incidence, extragastrointestinal stromal tumors are potentially malignant tumors and they present a high rate of recurrences. This, added to the fact that they are often asymptomatic until advanced stages, determines an unfavorable prognosis.

Case Report: We report a case of gastrointestinal stromal tumor located in the rectovaginal septum, which recurred after local excision; hence, a reintervention was needed.

Conclusions: A correct differential diagnosis between extragastrointestinal stromal tumors and other similar pathologies such as leiomyomas or schwannomas is imperative based on their histology and immunohistochemistry. The correct diagnosis of extragastrointestinal stromal tumors allows to start adequate treatment and follow-up, preventing recurrence that determines their poor prognosis.

In Brief

Extragastrointestinal stromal tumors must be considered in the differential diagnosis of a mass in the rectovaginal septum owing to their unfavorable prognosis if not properly treated.

Author Information

Gynecologic Oncology Unit, La Paz University Hospital, Madrid, Spain

Reprint requests to: Ignacio Zapardiel, MD, PhD, Gynecologic Oncology Unit, La Paz University Hospital, Paseo Castellana 261, 28046, Madrid, Spain. E-mail: ignaciozapardiel@hotmail.com

The authors have declared they have no conflicts of interest.

The authors did not receive financial support for this study.

Copyright © 2014 by the American Society for Colposcopy and Cervical Pathology