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Primary Tuberculosis of the Uterine Cervix: Keep It in Mind

Mandato, Vincenzo Dario MD, PhD; Sacchetti, Franco MD; Costagliola, Luigi MD, PhD; La Sala, Giovanni Battista MD

Journal of Lower Genital Tract Disease: April 2014 - Volume 18 - Issue 2 - p E29–E33
doi: 10.1097/LGT.0b013e31829a5572
Case Reports

Introduction Primary tuberculosis of the cervix is extremely rare, with only 20 cases reported in the English literature since 1949. Here we report the 21st case—an Italian woman with no risk factors.

Case A 50-year-old Italian nulliparous woman was referred to our gynecology unit for vaginal discharge. Her past history was negative. Colposcopy revealed an ulcerated lesion raising the suspicion of cervical cancer. A biopsy revealed a tuberculosis granuloma, and acid-fast bacillus was identified with Ziehl-Neelsen stain. As no other site of tuberculosis was found, primary cervical tuberculosis was diagnosed.

Conclusions Although rare in industrialized countries, cervical tuberculosis may affect even women without risk factors. It should thus be taken into account in the differential diagnosis of cervical cancer.

Cervical tuberculosis may affect even women without risk factors; thus, it should be taken into account in the differential diagnosis of cervical cancer.

Department of Obstetrics and Gynecology, Arcispedale S. Maria Nuova di Reggio Emilia - IRCCS, University of Modena and Reggio Emilia, Italy

The authors have declared they have no conflicts of interest.

Reprint requests to: Vincenzo Dario Mandato, Department of Obstetrics and Gynecology, Arcispedale S. Maria Nuova di Reggio Emilia-IRCCS, Italy. E-mail: dariomandato@virgilio.it

Copyright © 2014 by the American Society for Colposcopy and Cervical Pathology