Objective: To report the case of a patient with a large and symptomatic vulvar lesion, necessitating surgical excision.
Case: We report the case of a 57-year-old postmenopausal woman with a 6-month history of an enlarging vulvar lesion associated with vulvar pruritus. On examination, a pedunculated 7 × 5 × 4-cm soft tissue mass attached to the left labium majus was noted. Surgical excision was performed and histopathologic evaluation revealed variably dilated, submucosal vessels with thick muscular walls and intimal thickening, but without endothelial atypia or multilayering. These findings were consistent with a final diagnosis of arteriovenous malformation of the vulva.
Conclusions: Given the complex anatomy of the vulva, the differential diagnosis for vulvar vascular lesions can be challenging. Hence, surgical excision and histopathologic evaluation become imperative to distinguish them from other dermatologic and neoplastic conditions of the vulva.
Surgical excision and histopathologic evaluation of vulvar vascular lesions are imperative to distinguish them from other dermatologic and neoplastic conditions of the vulva.
Departments of 1Obstetrics and Gynecology and 2Pathology, Drexel University College of Medicine, Philadelphia, PA
Reprint requests to: Nigel Pereira, MD, Department of Obstetrics and Gynecology, 245 N 15th St, MS 495, 16th Floor, New College Building, Philadelphia, PA 19102. E-mail: Nigel.Pereira@drexelmed.edu
The authors declare they have no conflicts of interest.
Michael Mirmanesh is an MD candidate at Drexel University College of Medicine, Philadelphia, PA.
Presented as a poster at the College of American Pathologists Annual Meeting, September 2012, San Diego, CA.