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Vulvar Fibrous Hamartoma of Infancy: A Rare Case Report and Review of Literature

Monajemzadeh, Maryam MD1; Vasei, Mohammad MD1; Kalantari, Mehdi MD2; Montaser-Kouhsari, Laleh MD1; Taleb, Shanyandokht MD1

Journal of Lower Genital Tract Disease:
doi: 10.1097/LGT.0b013e31824e68fd
Original Articles
Abstract

Background: Fibrous hamartoma of infancy is a benign mesenchymal tumor occurring infrequently in children, typically involving the axilla.

Case Report: An 18-month-old girl with a history of right labium majus enlargement, on examination, had a hard mass that was found strictly adherent to subcutaneous tissue and overlying skin. Postexcision histological examination showed arranged spindle cells, adipose tissue, and nests of immature small cells in a myxoid background, consistent with fibrous hamartoma of infancy.

Conclusions: The main problem in the diagnosis is differentiating this lesion from soft tissue sarcomas, which require an aggressive therapeutic approach. Both surgeons and pathologists need to be aware of the existence of such benign condition in this unusual place to avoid unnecessary therapies.

Author Information

Departments of 1Pathology, and 2Pediatric Surgery, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran

Reprint requests to: Maryam Monajemzadeh, MD, Department of Pathology, Children’s Medical Center Hospital, Tehran University of Medical Sciences, Keshavarz Boulevard, Tehran, Iran. E-mail: monajemz@sina.tums.ac.ir

The authors declare there are no conflicts of interest.

©2013The American Society for Colposcopy and Cervical Pathology