Skip Navigation LinksHome > January 2013 - Volume 17 - Issue 1 > Vaginal Toxic Shock Reaction Triggering Desquamative Inflamm...
Journal of Lower Genital Tract Disease:
doi: 10.1097/LGT.0b013e3182656991
Original Articles

Vaginal Toxic Shock Reaction Triggering Desquamative Inflammatory Vaginitis

Pereira, Nigel MD1; Edlind, Thomas D. PhD2; Schlievert, Patrick M. PhD3; Nyirjesy, Paul MD1

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Objective: The study aimed to report 2 cases of desquamative inflammatory vaginitis associated with toxic shock syndrome toxin 1 (TSST-1)–producing Staphylococcus aureus strains.

Materials and Methods: Case report of 2 patients, 1 with an acute and 1 with a chronic presentation, diagnosed with desquamative inflammatory vaginitis on the basis of clinical findings and wet mount microscopy. Pretreatment and posttreatment vaginal bacterial and yeast cultures were obtained.

Results: Pretreatment vaginal bacterial cultures from both patients grew TSST-1–producing S. aureus. Subsequent vaginal bacterial culture results after oral antibiotic therapy were negative.

Conclusions: Desquamative inflammatory vaginitis may be triggered through TSST-1–mediated vaginal toxic shock reaction.

©2013The American Society for Colposcopy and Cervical Pathology


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