Skip Navigation LinksHome > January 2013 - Volume 17 - Issue 1 > Late Recurrence of Aggressive Angiomyxoma of the Vulva
Journal of Lower Genital Tract Disease:
doi: 10.1097/LGT.0b013e3182545d2f
Original Articles

Late Recurrence of Aggressive Angiomyxoma of the Vulva

Kiran, Gurkan1; Yancar, Semih1; Sayar, Hamide2; Kiran, Hakan1; Coskun, Ayhan1; Arikan, Deniz Cemgil1

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Objective: Aggressive angiomyxoma (AA) is found mainly in the pelvis and perineum, with a female-to-male ratio of approximately 6:1. Although it is a slow growing tumor, AA has a marked tendency to local recurrence with a low metastasis capacity. The study aimed to describe a case of vulvar angiomyxoma recurred almost 20 years after its initial surgery.

Materials and Methods: We report the case of a 57-year-old gravida 5 para 4 woman with vulvar AA arising from the left labium majus, which recurred 20 years after initial surgery. There was a nontender, solid, mobile mass on the left vulva, which was 25 x 30 cm on physical examination. A pelvic computed tomographic scan showed a mass measuring 26 x 10 x 14 cm originating from left vulvar region, which has a fatty tissue density.

Result: Under general anesthesia, total excision of the tumor was performed. Macroscopically, the tumor weighed 723 g and measured 33 x 20 x 10 cm. The histopathological examination of the specimen revealed a myxoid tumor with sparse infiltrates of spindle-shaped to stellate cells and vessels of varying sizes. The final histopathological diagnosis was AA.

Conclusions: Aggressive angiomyxoma may form extremely large tumors, and recurrence is not rare even many years after primary surgery.

©2013The American Society for Colposcopy and Cervical Pathology


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