Objective: This study aimed to compare cervical cancer screening by cervicography with screening by Pap test.
Materials and Methods: This was a comparative multicenter study of cervical cytology and cervicography. The cervicography (slides of the cervix) was taken after the Pap test was completed. In total, samples were collected from 1176 patients. Colposcopy with biopsy was considered the gold standard for the final diagnosis of lesions observed by the Pap test and cervicography. Statistical analysis was performed using the binomial test.
Results: In cases in which the Pap test was negative for cervical lesions, diagnosis by cervicography was positive in 15 cases of cervical intraepithelial neoplasia 1 (CIN 1) (p = .00052), in 1 case of CIN 2, in 1 case of CIN 3, and in 1 case of cancer. However, cervicography produced 3 false-positive results (p < .0001).
Conclusions: Cervicography may be used as a complementary screening method to the Pap test for cervical cancer.
This was a multicenter study that compared cervical cancer screening by cervicography with screening by Pap test. In total, 1176 samples were collected. Cervicography may be a complementary screening method for cervical cancer.
1Gynecology Department, Evangelic School of Medicine of Parana; 2Gynecology Department, Federal University of Parana; 3Gynecology Department, State University of Londrina, Parana, Brazil; and 4Gynecology Service, Clinique Saint Vincent, Liège, Belgium
Reprint requests to: Plinio Gasperin Jr., MD, Rua Sao Thomas de Aquino, 108 Curitiba CEP 80440-160 Brazil. E-mail: email@example.com
Research funding was provided by the following institutions: Evangelic School of Medicine of Parana, Federal University of Parana, State University of Londrina, and Clinique Saint Vincent, Liège.
The authors have no conflicts of interest.