Home Current Issue Previous Issues Published Ahead-of-Print Collections For Authors Journal Info
Skip Navigation LinksHome > July 2012 - Volume 16 - Issue 3 > Rates of Self-Reported Urinary, Gastrointestinal, and Pain C...
Journal of Lower Genital Tract Disease:
doi: 10.1097/LGT.0b013e3182562f1e
Original Articles

Rates of Self-Reported Urinary, Gastrointestinal, and Pain Comorbidities in Women With Vulvar Lichen Sclerosus

Berger, Mitchell B. MD, PhD1; Damico, Nicholas J. BS1; Menees, Stacy B. MD, MS2; Fenner, Dee E. MD1; Haefner, Hope K. MD3

Collapse Box

Abstract

Objective: The study aimed to determine the prevalences of comorbid disorders in women with vulvar lichen sclerosus.

Materials and Methods: A retrospective review of self-administered questionnaires regarding the health history of 308 women with lichen sclerosus seen at a vulvar clinic between 2006 and 2011 was performed. Responses to questions about urinary (overactive bladder [OAB], urinary incontinence [UI], and stress UI), gastrointestinal (inflammatory bowel diseases, constipation, and irritable bowel syndrome), thyroid dysfunction and pain (interstitial cystitis, fibromyalgia, temporomandibular joint disorder, and vulvar pain) disorders were collected. The percentage of subjects self-reporting each comorbidity was compared with the published prevalence in the general population using a single-value binomial test.

Results: Subject demographics (data presented as median [range] or percentage): age, 56.4 years (20.0–92.5); body mass index, 27.5 kg/m2 (17.4–53.1); parity 2 (0–10); white, 92.9%; and biopsy proven 65.6%. Prevalences of self-reported comorbidities in our subjects are as follows: OAB, 15.3%; UI, 38.6%; stress UI, 27.9%; inflammatory bowel diseases, 1.9%; constipation, 32.5%; irritable bowel syndrome, 19.5%; thyroid dysfunction, 33.1%; interstitial cystitis, 2.6%; fibromyalgia, 9.1%; temporomandibular joint disorder, 13.0%; and vulvar pain, 83.1%. The prevalence of each disorder is significantly different from that in the general population, with all p values ≤ .02.

Conclusions: Vulvar lichen sclerosus is associated with numerous bladder, bowel, and pain comorbidities. The prevalences of all of these disorders are higher in our subjects than the general population except OAB, which we find at approximately one third of the general population. Patients with lichen sclerosus should be screened for comorbidities that may affect their health and/or quality of life.

©2012The American Society for Colposcopy and Cervical Pathology

Login

Article Tools

Share

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.