Objective: Blue nevi are extremely rare in the vaginal canal and are suspicious for melanoma, especially when multiple lesions are present. We describe a woman with multiple blue nevi of the vagina.
Design: We describe 1 case of multiple blue nevi of the vagina.
Results: A 37-year-old woman, status after therapy for serous carcinoma of the ovary, presented with multiple blue to black macular lesions present throughout the vagina. Two of the lesions were examined by biopsy and demonstrated dendritic melanocytes. The patient has been closely followed, and the lesions remain unchanged.
Conclusions: Multiple vaginal blue nevi are an important differential diagnostic consideration for melanoma of the vagina. These lesions, however, are benign and require only clinical follow-up. Excision is unnecessary.