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Evaluation of the VITOM in Digital High-Definition Video Exocolposcopy

Vercellino, Giuseppe Filiberto MD1; Erdemoglu, Evrim MD1,2; Kyeyamwa, Sarah MD1; Drechsler, Inka MD1; Vasiljeva, Jekaterina MD1; Cichon, Guenter MD1; Schneider, Achim MD, MPH1

Journal of Lower Genital Tract Disease:
doi: 10.1097/LGT.0b013e3182102891
Original Articles
Abstract

Objective: Our aim was to present our initial clinical experience using a novel exoscopically based colposcopy system (VITOM) for the evaluation of cervical, vulvar, and vaginal diseases.

Materials and Methods: Women referred to the Charite Cervix Center, Charite University, Berlin, Germany, were included. Patients with abnormal Pap smear results, vulvar lesions, or a biopsy report of neoplasia of the lower genital tract were included into the study. The VITOM was used for colposcopic evaluation and directed biopsies. Colposcopic findings were reported according to the criteria of the Committee on Nomenclature of the International Federation of Cervical Pathology and Colposcopy. Histologic diagnosis was described as normal, low-grade lesion, high-grade lesion (including cervical intraepithelial neoplasia 2,3, vulvar intraepithelial neoplasia 2,3, vaginal intraepithelial neoplasia 2,3), or cancer.

Results: We recruited 76 patients (54 with cervical, 4 with vaginal, and 18 with vulvar disease) to the prospective study. Four patients were pregnant. Of patients with cervical disease, 29% had a history of previous conization and 3.7% had a history of trachelectomy. The sensitivity, specificity, negative predictive value, and positive predictive value of the VITOM for cervical intraepithelial neoplasia 2, 3 were 90%, 77%, 90% and 77%, respectively. Concordance of exocolposcopic impressions and histologic results was higher in high-grade lesions (K = 0.68, 95% CI = 0.32-0.87, p < .001) than in low-grade lesions (K = 0.41, 95% CI = 0.1-0.41, p < .05).

Conclusions: Exocolposcopy with the VITOM is accurate and shows good correlation to histologic findings in high-grade disease of the lower genital tract. The potential advantages include patient and trainee involvement in examination, decision making, and documentation.

In Brief

Exocolposcopy with the VITOM is accurate and shows good correlation to histologic findings in high-grade cervical disease of the lower genital tract.

Author Information

1Department of Gynecology and Gynecologic Oncology, Charite University, Berlin, Germany; and 2Department of Gynecology and Gynecologic Oncology, Süleyman Demirel University, Isparta, Turkey

Reprint requests to: Achim Schneider, MD, MPH, Department of Gynecology and Gynecologic Oncology, Charite University, Hindenburgdamm 30, Berlin, Germany. E-mail: achim.schneider@charite.de

©2011The American Society for Colposcopy and Cervical Pathology