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Chronic Granulomatous Inflammation of the Vulva: An Unusual Presentation With Diagnostic and Therapeutic Difficulties

Ghosh, Donna MBBS, BSc1; Woodrow, Sarah MRCP2; Mathew, Joe MRCPath3; Lopes, Alberto FRCOG1; Das, Nagindra MRCOG1

Journal of Lower Genital Tract Disease:
doi: 10.1097/LGT.0b013e318216aaac
Case Reports

Inflammation of the vulva can present as a manifestation of a localized problem or as part of a systemic disorder. Granulomatous vulvitis is a rare inflammatory condition that has histologic similarities to Crohn disease. Clinically, it presents with painless, chronic relapsing erythema, and edema, typically affecting the genital area. We report a case of extensive granulomatous vulvitis in a patient with no gastrointestinal evidence of Crohn disease. We describe difficulties with diagnosis and limitations in the treatment of isolated vulval granulomatous disease and aim to promote earlier recognition of the disease.

In Brief

A case report of an unusual vulval dermatosis that presents a management dilemma.

Author Information

Departments of 1Obstetrics & Gynaecology, 2Dermatology, and 3Histopathology, Royal Cornwall Hospital, Truro, Cornwall, UK

Reprint requests to: Donna Ghosh, MBBS, BSc, Department of Obstetrics & Gynaecology, Royal Cornwall Hospital, Treliske, Cornwall, TR13 LJ, UK. E-mail:

©2011The American Society for Colposcopy and Cervical Pathology