Skip Navigation LinksHome > April 2008 - Volume 12 - Issue 2 > Complete Resolution of Paget Disease of the Vulva With Imiqu...
Journal of Lower Genital Tract Disease:
doi: 10.1097/LGT.0b013e31815a58a5
Original Articles

Complete Resolution of Paget Disease of the Vulva With Imiquimod Cream

Hatch, Kenneth D. MD; Davis, John R. MD

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Abstract

Extra mammary Paget disease (EMPD) is a neoplastic disease of apocrine gland bearing skin. Surgical excision is the standard of care for EMPD; however, it is accompanied by recurrence in more than 60% of the patients. Recently, imiquimod cream has been reported to induce complete responses in primary or recurrent EMPD. We report on 2 women with vulva EMPD who achieved biopsy-confirmed resolution of their disease after topical application of imiquimod 5% cream.

©2008The American Society for Colposcopy and Cervical Pathology

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